Comparison of repeated transcranial stimulation and transcranial direct-current stimulation on primary motor cortex excitability and inhibition: A pilot study

V, Cabibel; M, Muthalib; J, Froger; S, Perrey

Abstract:

Repeated transcranial magnetic stimulation (rTMS) is a well-known clinical neuromodulation technique, but transcranial direct-current stimulation (tDCS) is rapidly growing interest for neurorehabilitation applications. Both methods (contralesional hemisphere inhibitory low-frequency: LF-rTMS or lesional hemisphere excitatory anodal: a-tDCS) have been employed to modify the interhemispheric imbalance following stroke. The aim of this pilot study was to compare aHD-tDCS (anodal high-definition tDCS) of the left M1 (2 mA, 20 min) and LF-rTMS of the right M1 (1 Hz, 20 min) to enhance excitability and reduce inhibition of the left primary motor cortex (M1) in five healthy subjects. Single-pulse TMS was used to elicit resting and active (low level muscle contraction, 5% of maximal electromyographic signal) motor-evoked potentials (MEPs) and cortical silent periods (CSPs) from the right and left extensor carpi radialis muscles at Baseline, immediately and 20 min (Post-Stim-20) after the end of each stimulation protocol. LF-rTMS or aHD-tDCS significantly increased right M1 resting and active MEP amplitude at Post-Stim-20 without any CSP modulation and with no difference between methods. In conclusion, this pilot study reported unexpected M1 excitability changes, which most likely stems from variability, which is a major concern in the field to consider.

Patologie/Applicazioni:

• Stimolazione Magnetica Transcranica (TMS)
• Stimolazione elettrica transcranica (TES)

Anno:

2018

Tipo di pubblicazione:

Articolo

Parola chiave:

stimolazione elettrica transcranica; stimolazione magnetica transcranica; neuromodulazione; hd-tdcs

Testata scientifica:

Movement e Sport Sciences

Nota:

Studio pilota di comparazione tra gli effetti di HD-tDCS e rTMS nell'aumento dell'eccitabilità corticale dell'area motoria (M1). Sui soggetti sono state effettuate sessioni di tDCS e rTMS e successivamente sono stati registrati i potenziali evocati motori. Entrambe le metodiche comportano un aumento dell'ampiezza della risposta evocata MEP, indice di cambiamento dell'eccitabilità corticale.

DOI:

https://doi.org/10.1051/sm/2018001