Pubblicazioni

Optimization of Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex for Tinnitus: A Non-Linear Dose-Response Effect

GS, Shekhawat; S, VAnneste

Abstract:

Neuromodulation is defined as the process of augmenting neuroplasticity via invasive or non-invasive methods. Tinnitus is the perception of sound in the absence of its external source. The objective of this study was to optimize the parameters of transcranial direct current stimulation (tDCS) of dorsolateral prefrontal cortex (DLPFC) for tinnitus suppression. The following factors were optimized in the dose-response design (n = 111): current intensity (1.5 mA or 2 mA), stimulation duration (20 min or 30 min), and number of stimulation sessions (2, 4, 6, 8, or 10), with a 3–4 day washout period between each session. Participants underwent a minimum of 2 sessions in 1 week or maximum of 10 sessions in 5 weeks’ time. Tinnitus loudness was measured in pre-post design using a 10-point numeric rating scale. There was a significant reduction in tinnitus loudness after tDCS of DLPFC. There was no significant difference between the intensity and duration of stimulation. As the number of sessions increased, there was a higher reduction in the tinnitus loudness; however, this effect plateaued after 6 sessions.

Patologie/Applicazioni:

• Stimolazione elettrica transcranica (TES)
• Tinnitus

Anno:

2018

Tipo di pubblicazione:

Articolo

Parola chiave:

acufeni; corteccia prefrontale; tinnitus; stimolazione elettrica transcranica

Testata scientifica:

Scientific Reports

Nota:

Ottimizzazione del numero di sessioni richieste nel trattamento per la soppressione del tinnito con la stimolazione transcranica in corrente continua (tDCS) con montaggio a corona sulla corteccia prefrontale dorsolaterale (DLPFC). Ideali 2 sessioni a settimana per 6 settimane con correnti di 1,5 mA per 20 minuti, pausa di 3-4 giorni tra una seduta e l'altra. Prodotto consigliato per questa applicazione: gamma StarStim.

DOI:

10.1038/s41598-018-26665-1